KMID : 0370220010450060701
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Yakhak Hoeji 2001 Volume.45 No. 6 p.701 ~ p.707
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Inhibitory Effects of Crude Polysaccharide of Water Extract of Artemisia iwayomogi Kitamura on Melanin Biosynthesis
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õÇöÀÚ/Chun HJ
¾Èº´¿ë/ÇÑÁ¾Çö/¿ì¿øÈ«/Ahn BY/Han JH/Woo WH
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Abstract
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Melanogenesis is a physiological process resulting in the synthesis of melanin pigment. We investigated the inhibitory effect of crude polysaccharide of water extract of Artemisia iwayomogi Kitamura(AI) on melanin biosynthesis in B16/F10 melanoma cells. Crude polysacchride of water extract of Artemisia iwayomogi Kitamura signifcantly inhibited tyrosinase activity and melanin contents with or without ¥á-MSH in vitro. Melanin contents and tyrosinase activity were decreased in a dose-dependent manner. These results show that crude polysaccharide of water extract of Artemisia iwayomogi Kitamura Could be developed as skin whitening components of cosmetics.
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